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产品目录

重组人Cyclophilin A(CYPA)图片
产品货号:
JN1606
中文名称:
重组人Cyclophilin A(CYPA)
英文名称:
Recombinant Human Peptidyl-prolyl Cis-trans Isomerase A
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Glu165表达纯化得来。

Cyclophilin A/CYPA质量控制:>95%(还原性SDS-PAGE)

Cyclophilin A/CYPA制剂:液体

Cyclophilin A/CYPA保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于Cyclophilin A/CYPA
Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
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